WebMetal-free γ-trifluoromethylation of Baylis–Hillman acetates is reported using Langlois’ reagent under visible light photoredox catalysis. WebIodonium ylides have found synthetic application as efficient carbene precursors, especially useful as reagents for cyclopropanation of alkenes and preparation of heterocyclic …
The dual role of thiourea in the thiotrifluoromethylation of alkenes
WebVarious salts of 3-allyl-1,1-dibenzyl-2-ethyl-isothiourea, 1 (hydrochloride), 2 (hydrobromide), and 3 (hydroiodide), were synthesized. Ca-blocking properties of these salts were studied. Comparative analysis of the potentiating effects of 3 and cyclothiazide (CT) on transmembrane currents caused by kainic acid (KA) and glutamate in Purkinje neurons … crowdmark creating exam tutorial
The dual role of thiourea in the …
WebMar 1, 2024 · A light-promoted methodology for the iodotrifluoromethylation of alkenes was developed. For the first time a Togni reagent was exploited as the source of both the CF 3 group and iodine atom. Preliminary mechanistic studies suggest that both CF 3 I and 2-iodobenzoic acid are direct sources of the iodine atom that is transferred to the products. WebJan 1, 2015 · Thiotrifluoromethylation reaction reported by Shen et al. Full size image. 2.1.2 Carbon–Carbon Bond Formation. Stereoselective carbon–carbon bond formations with hypervalent iodine reagents are also prominently described in the literature. Direct asymmetric α-arylation reactions are not easy to perform. WebSep 29, 2024 · This Perspective describes the development of a family of copper(II)-catalyzed alkene difunctionalization reactions that enable stereoselective addition of amine derivatives and alcohols onto pendant unactivated alkenes to provide a range of valuable saturated nitrogen and oxygen heterocycles. 2-Vinylanilines and related substrates … crowdmark login utm