Podxl endothelial
WebNational Center for Biotechnology Information WebOct 1, 2004 · Only one case of HCC showed negative staining. PODXL was negative in all five normal livers and 8/10 paired cirrhotic tissues. Only two cirrhotic livers showed focal sinusoidal staining for PODXL. CD34, the other endothelial gene in cluster I, showed a staining pattern that was similar to PODXL . In contrast to the staining pattern of PODXL …
Podxl endothelial
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WebApr 22, 2024 · a, Fine-cluster analysis of synovial tissue endothelial cell scRNA-seq data: arterial PODXL + (orange) and venous DARC + (blue) subtypes are highlighted in UMAP projection. All non-vascular ... WebIn human Henle-407 epithelial cells, typhoid toxin interacts with Podocalyxin-like protein 1 (PODXL), a member of the CD34 sialomucin protein family, which localizes to the apical side of epithelial cells and is also expressed in vascular endothelial cells [25,26]. In addition, in macrophages, ...
WebApr 7, 2024 · The expression of PROX1 and vascular endothelial growth factor C (VEGFC) was found to be closely linked to PDPN. The expression of CD14 was found to be highly correlated with the distribution of markers for lymphangiogenesis (Figure 8A,B ), reflecting that CD14+ Mono/MΦ enter the vicinity of the glomerulus through newly forming … WebFeb 27, 2024 · Podocalyxin, a sialoglycoprotein, is thought to be a major component of this glycocalyx. By screening human renal cortex and heart cDNA libraries with a rabbit …
WebOct 10, 2014 · Conditional deletion of the Podxl locus in endothelial cells. ( A ) Schematic representation of the Podxl transgenic allele, floxed allele (Podxl F/F ) and deleted allele ( Podxl D F/F ). WebDec 1, 2024 · Podocalyxin (PODXL), also known as TRA-1-60 and TRA-1-81 antigens, is a highly N - or O-glycosylated type I transmembrane protein with a molecular weight of 150,000–200,000 [[1], [2], [3], [4]], and is used as pluripotent stem …
WebJun 1, 2024 · Podocalyxin (PODXL) is expressed in renal podocytes and vascular endothelium.6 In BMECs, PODXL is localized on the luminal side of the plasma membrane. 7 PODXL is a type I transmembrane protein with a short cytoplasmic tail.
WebJun 1, 2024 · Podocalyxin (PODXL) is a highly sialylated transmembrane protein that is expressed on the luminal membrane of brain microvascular endothelial cells. To clarify … terratech gillette wyWebJun 10, 2024 · It is unknown, however, how various lesions in PODXL contribute to these disparate disease pathologies. Here we generated two mouse stains: one that deletes … trident health moncks cornerWebOct 18, 2024 · A Angpt1-GFP staining showing expression in PDGFRB-positive tissues of the uveal tract.As expected, no Angpt1 expression was detected in PODXL-positive … terratech gmbhWebDec 30, 2024 · Results: Eleven cell types were identified, with immune-related cell types (T cells, natural killer cells, macrophages, and mast cells) distributed in the left (early) branch of the pseudotime tree, cancer stem cells, and CRISPLD2+ cells as intermediate cell types, and classic disease-related cell types (fibroblasts, smooth muscle cells, myofibroblasts, and … trident hermon maineWebCD34 family proteins are expressed by endothelial cells and hematopoietic precursors. PODXL is well known to be associated with invadopodia formation and to promote the epithelial-mesenchymal transition, tumor migration and invasion. PODXL expression was correlated with poor survival of cancer patients. However, the role of PODXL2 in cancer … trident healthcare ltdWebMay 25, 2024 · The endothelium is metabolically active and has been found to play a key role in processes governing inflammation, leukocyte trafficking, gas and nutrient … trident highschool parent portalWebAbstract. The highly sialoglycosylated extracellular domain of podocalyxin (Podxl) is a constituent of the endothelial glycocalyx of most blood vessels but it is unknown if Podxl … terratech group