Dihydrodipicolinate synthase
Webnpl N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) [ (Gulf pipefish)] Gene ID: 125965861, updated on 3-Mar-2024. Summary Other designations. N-acetylneuraminate lyase WebJan 27, 2016 · The enzyme dihydrodipicolinate reductase (DHDPR) is a component of the lysine biosynthetic pathway in bacteria and higher plants. DHDPR catalyzes the NAD(P)H dependent reduction of 2,3-dihydrodipicolinate to the cyclic imine L-2,3,4,5,-tetrahydropicolinic acid. ... Dihydrodipicolinate synthase from Escherichia coli: pH …
Dihydrodipicolinate synthase
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WebNov 9, 2004 · The three-dimensional structure of the enzyme dihydrodipicolinate synthase (KEGG entry Rv2753c, EC 4.2.1.52) from Mycobacterium tuberculosis (Mtb-DHDPS) was determined and refined at 2.28 A (1 A=0.1 nm) resolution. The asymmetric unit of the crystal contains two tetramers, each of which we propose to be the functional … http://pseudomonas.umaryland.edu/PAMDB?db=PaMet&query=&page=45
4-Hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7, dihydrodipicolinate synthase, dihydropicolinate synthetase, dihydrodipicolinic acid synthase, L-aspartate-4-semialdehyde hydro-lyase (adding pyruvate and cyclizing), dapA (gene)) is an enzyme with the systematic name L-aspartate-4-semialdehyde hydro-lyase (adding pyruvate and cyclizing; (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinate-forming). This enzyme catalyses the following chemical reaction WebMar 1, 1997 · Four inhibitors of the lysine biosynthetic enzyme dihydrodipicolinate synthase (DHDPS) were examined for their effects on the late blight fungus Phytophthora infestans.One of these compounds, dipicolinic acid, reduced mycelial growth of P. infestans by 61% and completely controlled blight infection of leaf discs when used at 1 mM. The …
WebThe use of a lysine-overproducing strain ofLactobacillus plantarumin food or feed fermentations may lead to the production of lysine-rich products. The availability of functional genes and information on the regulation of lysine biosynthesis are WebOct 5, 2024 · Dihydrodipicolinate synthase (DHDPS) is an allosteric enzyme, which catalyzes the first unique step of lysine biosynthesis in prokaryotes, higher plants and …
WebNov 20, 2024 · In higher plants, the reaction catalyzed by dihydrodipicolinate synthase (DHDPS) is the first committed step in the biosynthesis of lysine and is subject to regulation by lysine through feedback inhibition. Here, we report enhancement of lysine content in C. sativa seed via expression of a feedback inhibition-insensitive form of DHDPS from ...
WebDescription: L-2,3-Dihydrodipicolinate is involved in the lysine biosynthesis pathway. L-2,3-Dihydrodipicolinate is produced from a reaction between pyruvate and L-aspartate-semialdehyde, with water as a byproduct. The reaction is catalyzed by … map ashland msWebIn plants and bacteria, the branch point of (S)-lysine biosynthesis is the condensation of (S)-aspartate-beta-semialdehyde [ (S)-ASA] and pyruvate, a reaction catalyzed by dihydrodipicolinate synthase (DHDPS, EC 4.2.1.52) [8]. Role of arginine 138 in the catalysis and regulation of Escherichia coli dihydrodipicolinate synthase [8]. kraft coachingWebJul 3, 2005 · Dihydrodipicolinate synthase (E. coli)- mutant R138A. In plants and bacteria, the branch point of (S)-lysine biosynthesis is the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate, a reaction catalyzed by dihydrodipicolinate synthase (DHDPS, EC 4.2.1.52). map ashland county wiWebFeb 9, 1995 · The dihydrodipicolinate synthase monomer is composed of two domains. Each polypeptide chain is folded into an 8-fold alpha/beta barrel and a C-terminal alpha-helical domain comprising residues 224 to 292. The fold is similar to that of N-acetylneuraminate lyase. The active site lysine 161 is located in the alpha/beta barrel … map ashington sussexWebDihydrodipicolinate synthase (DHDPS) catalyzes the condensation of pyruvate with l-aspartate β-semialdehyde. It is the first enzyme unique to the diaminopimelate pathway … map ashland mtWebJan 18, 2013 · Dihydrodipicolinate synthase (DHDPS, EC 4.2.1.52) is the first enzyme of the lysine-specific branch of the biosynthetic pathway of the aspartate-derived amino acids. It catalyses the condensation of pyruvate with the common precursor L-aspartate-β-semialdehyde ... kraft code services shillington paWebKelsey Woellmer CIBER 103 Inhibition of Dihydrodipicolinate Synthase Through the Addition of 3-Iodopropionic Acid Tyler Cook CIBER 105 Evaluation of Statistical Techniques to Normalize Urinary Metabolomic Data Parker Brecheen CIBER 107 Elucidation of Novel Bile Salt Sensitivity in Escherichia coli map ashland ne