Cdk4 antibody
WebApr 14, 2024 · Cyclin-dependent kinase 4 (CDK4) ... In recent decades, immunotherapy consisting of monoclonal antibodies (anti-PD-1 or anti-PD-L1) has been widely used in breast cancer patients [245,246]. Sigma 1 receptor (S1R) is a unique drug-binding site that is commonly expressed in malignant breast epithelial cells and breast cancer cells . WebImmunoprecipitation - Anti-Cdk4 antibody (ab226474) Cdk4 was immunoprecipitated from HEK-293T (human epithelial cell line from embryonic kidney transformed with large …
Cdk4 antibody
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Webprotein. The dilution of anti-cdk4 and anti-D1 antibodies (Santa Cruz Biotechnology, Santa Cruz, CA) was 1:100 and 1:50 respec-tively. The dilution of anti-p16 (Pharmingen) was 1:500. After treatment with secondary biotinylated antibody and sABC com-plex, the slides were developed in 3-amino-9-ethylcarbazole and counterstained with hematoxylin.
Webcyclin dependent kinase 4 , CMM3 , PSK-J3 Background The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the … WebProduced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply. Alexa Fluor® 488 Rabbit monoclonal [EPR2513Y] to Cdk4. Suitable for: ICC/IF, Flow Cyt (Intra) Knockout validated. Reacts with: Human. Conjugation: Alexa Fluor® 488. Ex: 495nm, Em: 519nm.
WebThe active complex of cyclin D/CDK4 targets the retinoblastoma protein for phosphorylation, allowing the release of E2F transcription factors that activate G1/S-phase gene expression (3). Levels of cyclin D protein drop … WebJan 14, 2024 · Write a review Ask a question. Cdk4 Antibody (C-22) is a rabbit polyclonal IgG; 100 µg/ml; or goat IgG; 200 µg/ml, sc-260-G. epitope mapping at the C-terminus of Cdk4 of mouse origin. Discontinued polyclonal antibody. See product citations (568)
WebCDK4: A gene on chromosome 12q14 that encodes a Ser/Thr kinase, which is the catalytic subunit of the cyclin-dependent protein kinase complex. CDK2 activity is restricted to the …
WebProduct Description. Rabbit anti CDK4 antibody recognizes the cyclin-dependent kinase 4 (CDK4) also known as cell division protein kinase 4 or PSK-J3. CDK4 is a member of the serine/threonine protein kinase family … lilows newborn nurseryWebCDK4 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. Protein Information; Name : CDK4: Function : Ser/Thr-kinase component of cyclin D-CDK4 (DC) complexes that phosphorylate and inhibit members of the retinoblastoma (RB) protein family including RB1 and regulate the cell-cycle during … hotels in westboro ottawaWebAll lanes : Anti-Cdk4 antibody [EPR4513-54-3] (ab108355) at 1/1000 dilution (unpurified) Lane 1 : Human osteosarcoma cells - control, non-targeting siRNA Lane 2 : Human osteosarcoma cells - siRNA for CDK4 Lysates/proteins at 20 µg per lane. Secondary All lanes : HRP-conjugated goat anti-rabbit IgG polyclonal at 1/2000 dilution lilo writingWebImmunohistochemistry-Paraffin: CDK4 Antibody [NBP1-31308] - Human gastric cancer, using CDK4 antibody at 1:500 dilution. Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min. hotels in weobley herefordshireWebCdk4 is a member of the Ser/Thr protein kinase family. It is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. Cdk4 is a catalytic subunit of the protein kinase complex that is important for cell … lilo yellow dressWebRabbit anti Human CDK4 antibody recognizes cyclin-dependent kinase 4, also known as cell division protein kinase 4. The protein encoded by CDK4 is a member of the Ser/Thr protein kinase family. This protein is highly … liloy beach resortWebAnti-CDK4 antibodies are offered by a number of suppliers. This target gene encodes the protein 'cyclin dependent kinase 4' in humans and may also be known as CMM3, PSK-J3, and cell division protein kinase 4. Structurally, the protein is reported to be 33.7 kilodaltons in mass. Based on gene name, fly, canine, porcine, monkey, mouse and rat ... hotels in westborough mass